Adderall Overdose: Signs, Risks and Treatment

Written by Melissa Carmona

& Medically Reviewed by Jenni Jacobsen, LSW

Medically Reviewed

Last updated: 07/15/2020

This article was reviewed by a medical professional to guarantee the delivery of accurate and up-to- date information. View our research policy.

Editorial Policy

Medically Reviewed by Jenni Jacobsen, LSW, PHD

View our editorial policy
If you or a loved one is struggling with addiction, help is available. Speak with a Recovery Advocate by calling (561) 340-7269 now.

Adderall overdose occurs when people misuse the drug or mix it with other drugs, and symptoms can include heart attack, seizures, coma or even death.

An Adderall overdose can occur when someone takes more of the medication than their body can handle, and the results can be dangerous and even deadly. People who misuse Adderall are more likely to overdose than those who don’t. There’s a high potential for Adderall abuse due to the physical and psychological dependence the drug can cause, which is why it is classified as a Schedule II drug.

Adderall affects people differently depending on the medications they take, their health history and their ability to process medication. People with any of the following health conditions should avoid taking Adderall until they’ve discussed the prescription with their doctor first:

  • Heart problems
  • Glaucoma
  • Thyroid conditions
  • High blood pressure
  • Depression
  • Extreme anxiety or anxiety disorders
  • Any mental illness
  • Vascular disease
  • Hardening of the arteries
  • History of drug misuse
  • History of seizures
  • Liver disease
  • Kidney disease
  • Tourette’s syndrome
  • Poor circulation
  • Epilepsy

Signs of Adderall Overdose

Many factors influence what happens during an Adderall overdose. These include how sensitive a person is to the medication, how much they took and whether they also used other substances. Adderall overdose symptoms may be mild or severe, and signs include:

  • Hyperactivity and aggressiveness
  • Confusion
  • Headaches
  • Nausea and vomiting
  • Rapid breathing
  • Stomach cramps
  • Hallucinations
  • High fever
  • Tremors, seizures, and convulsions
  • High blood pressure
  • Heart attack
  • Death

If someone experiences any of these symptoms while taking Adderall, it is important to seek emergency medical treatment immediately. If left untreated, even mild symptoms can eventually become serious or life-threatening.

Adderall Overdose Statistics

Because it improves the ability to focus and concentrate, many high school and college students misuse Adderall. Many feel it helps them study and perform better on their schoolwork. In 2018, approximately 4.6% of 12th graders reported misusing the drug within the last year. This rate of misuse is slightly higher than for opiates like Vicodin but lower than for sedatives and tranquilizers.

High school students are not the only ones abusing Adderall. One study showed that between 2006 and 2011, there was a 67% increase in adults abusing Adderall, as well as a 156% increase in emergency department treatment for issues related to Adderall abuse. Most of those who abused the drug obtained it from a relative or friend.

Causes of Adderall Overdose

The amount of Adderall it takes to overdose varies from person to person. The typical dose that doctors prescribe ranges from 2.5 mg to 60 mg, depending on factors such as age and health conditions. Overdose is typically caused by misuse, which occurs when someone:

  • Takes more than their doctor prescribed
  • Takes Adderall that wasn’t prescribed to them
  • Takes the drug recreationally

Substance Interactions

An overdose can also occur when someone mixes Adderall with other substances, including other prescription medications and illicit drugs. This is especially true for alcohol. Some people take Adderall when they plan to drink because the drug can help mask the effects of alcohol, preventing them from feeling too drunk. This can lead to alcohol poisoning.

Mixing Adderall and marijuana can also have serious consequences, especially if someone already has a heart condition. The combination of the two drugs increases the risk of irregular heartbeat, rapid heartbeat and heart attack.

Mixing Adderall and cocaine is even more dangerous. This is because both drugs are stimulants, and using them together can amplify the stimulating effects of each drug. While taking the two together may increase feelings of pleasure and energy, it puts stress on the cardiovascular system and can lead to chest pain, high blood pressure, heart attack and stroke.

Other substances that may interact with Adderall and lead to an overdose or other adverse reaction include:

  • Some acid-reducing drugs
  • Some monoamine oxidase inhibitors (MAOIs)
  • Certain antidepressants
  • Some opioids
  • Lithium
  • Certain vitamins and supplements
  • Caffeine

Before people begin taking Adderall, they should always let their doctor know if they’re taking any other medications, including natural supplements and vitamins.

Adderall Overdose Duration

The duration of overdose symptoms generally depends on how long it takes to get medical help. The quicker a doctor treats the symptoms, the quicker a person can get through the Adderall overdose timeline. Once someone has completed overdose treatment, however, he or she may experience withdrawal symptoms.

During the first three days of withdrawal from Adderall, people may feel tired or depressed and they may sleep more. They may experience headaches, mood swings, body aches, paranoia and trouble concentrating. Some withdrawal symptoms can last for a few months, so it’s best to seek help when ending Adderall use.

Are you or a loved one struggling with addiction?

Our Recovery Advocates are available 24/7 to help.

Adderall Overdose Complications

Complications caused by an Adderall overdose are typically related to the cardiovascular system. These include:

  • Rapid heartbeat
  • Irregular heartbeat
  • High blood pressure
  • Poor circulation
  • Heart attack
  • Stroke

A person experiencing any of these side effects should go to the emergency room immediately, even if symptoms don’t seem life-threatening. Prompt treatment can help prevent long-term complications.

Adderall Overdose Prevention

The best way to avoid an Adderall overdose is to take the medication exactly as the doctor prescribes it. Never take more than the prescription calls for, and always follow the directions the doctor or pharmacist provides. If any questions or adverse side effects arise, it is vital to contact a doctor.

Never take anyone else’s prescription, and never use Adderall as a recreational drug or as a means to get high. Most importantly, never combine Adderall with any other prescription drugs without a doctor’s permission. Avoid taking Adderall with alcohol and illicit drugs like cocaine and marijuana.

What to Do for an Adderall Overdose

If an Adderall overdose is suspected, it’s important to call 911. In the case of an overdose, paramedics can transport a person to the hospital quickly, and doctors can work to help counteract the overdose and treat emerging symptoms. If possible, let the paramedics and doctors know how much Adderall was taken and whether there’s a history of Adderall misuse.

Typical Adderall overdose treatment might include pumping the stomach, giving activated charcoal, providing sedatives for agitation and administering IV fluids to prevent dehydration. Once the symptoms are under control, doctors may opt to keep the patient in the hospital for a few days to monitor his or her health. It may also be necessary to provide treatment for any cardiovascular symptoms, such as elevated blood pressure or heart attack.

If you or a loved one has a problem with Adderall misuse or addiction, The Recovery Village Palm Beach at Baptist Health is here to help. Located in Palm Beach County in South Florida, we provide both inpatient and outpatient rehabilitation services in a calm and peaceful setting. Contact us today to learn more and find a program that is suitable for your situation.

View Sources

National Institute on Drug Abuse. “What are prescription stimulants?” June 2018. Accessed June 27, 2020.

United States Department of Justice: Diversion Control Division. “Controlled Substance Schedules.” Accessed June 27, 2020.

U.S. National Library of Medicine. “ADDERALL XR- dextroamphetamine sulfate, dextroamphetamine saccharate, amphetamine sulfate and amphetamine aspartate capsule, extended release.” July 17, 2019. Accessed June 27, 2020.

Drugs.com. “Adderall.” April 25, 2019. Accessed June 27, 2020.

Medical News Today. “Adderall (Amphetamine/Dextroamphetamine).” August 28, 2018. Accessed June 27, 2020.

Nall, Rachel. “Coping with an Adderall Crash.” Medical News Today, August 13, 2018. Accessed June 27, 2020.

National Institute on Drug Abuse. “Monitoring the Future 2018 Survey Results.” December 17, 2018. Accessed June 27, 2020.

Lian-Yu Chen, et al. “Prescriptions, Nonmedical Use, and Emergency Department Visits Involving Prescription Stimulants.” Journal of Clinical Psychiatry, 2016. Accessed June 27, 2020.

Authorship